UBE2L3 Protein

Produktnummer ABIN7939707

Dieses Recombinant UBE2L3-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für UBE2L3 Protein (ABIN7939707)

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant UBE2L3 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant UBE2L3 protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Andere Bezeichnung: UBE2L3

Hintergrund:

Protein Background: UBE2L3 (Ubiquitin-conjugating enzyme E2 L3) also known as E2-F1, L-UBC, UBCH7 and UbcM4. UBE2L3 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. It has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

Short Description: Recombinant UBE2L3 protein that includes full length of human UBE2L3 protein (accession number NP_003338.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 20.02 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

Aliases: Ubiqutin conjugating enzyme E2 L3, E2-F1, L-UBC, UBCH7, UbcM4, UBCE7