Dnmt2 Protein

Produktnummer ABIN7939655

Dieses Recombinant Dnmt2-Protein wird in Baculovirus infected Insect Cells produziert.

Kurzübersicht für Dnmt2 Protein (ABIN7939655)

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant DNMT2 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant DNMT2 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Andere Bezeichnung: DNMT2

Hintergrund:

Protein Background: DNMT2 (tRNA (cytosine(38)-C(5))-methyltransferase), a member of the DNA methyltransferase superfamily, catalyzes the formation of 5-methylcytosine at position 38 in the anticodon loop of tRNAs DNMT2 regulates many cellular biological processes, especially the production of tRNA derived fragments and intergenerational transmission of paternal metabolic disorders to offspring. Moreover, DNMT2 is closely related to human cancers.

Short Description: Recombinant DNMT2 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_004403.1) with an N-terminal FLAG tag. The molecular weight of DNMT2 is 45.9 kDa.

Aliases: TRNA Aspartic Acid Methyltransferase 1, RNMT1, DNA (Cytosine-5)-Methyltransferase-Like Protein 2