TOP2B Protein

Produktnummer ABIN7939649

Recombinant TOP2B-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für TOP2B Protein (ABIN7939649)

Target: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant TOP2B protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant TOP2B protein is supplied in 25 mM HEPES pH 7.5, 500 mM NaCl,500 mM KCl,10 % glycerol, 1 mM MgCl2,0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Andere Bezeichnung: TOP2B

Hintergrund:

Protein Background: TOP2B (DNA topoisomerase 2-beta ) is key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Plays a role in B-cell differentiation.

Short Description: Recombinant TOP2B protein was expressed in a baculovirus expression system as the full length protein (accession number NP_001059.2) with an N-terminal FLAG tag. The molecular weight of TOP2B is 183.93 kDa.

Aliases: DNA topoisomerase 2-beta, Top2beta, TOPIIB, Topoisomerase II, BILU