SETD5 Protein (AA 185-416)

Produktnummer ABIN7939562

Dieses Recombinant SETD5-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für SETD5 Protein (AA 185-416) (ABIN7939562)

Target: SETD5 (SET Domain Containing 5 (SETD5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Enzyme Kinetics (EK), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 185-416

Verwendungszweck: Recombinant SETD5 (185-416) protein

Anwendungsinformationen

Applikationshinweise: Recombinant SETD5 (185-416) protein is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant SETD5 (185-416) protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol and 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: SETD5 (SET Domain Containing 5 (SETD5))

Andere Bezeichnung: SETD5

Hintergrund:

Protein Background: SETD5 (SET Domain Containing 5), based on sequence similarity, is a member of SET domain proteins, and might displays histone methyltransferase activity in vitro. It was reported to monomethylate 'Lys-9' of histone H3 in vitro. The physiological significance of this activity is unclear and its activity has yet to be determined. SETD5 is a probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. According to researchers, it may act as a regulator of histone acetylation during gene transcription.

Short Description: Recombinant SETD5 (185-416) protein that includes amino acids 185-416 of human SETD5 protein (accession number NP_001073986.1) was expressed in E.coli and contains an N-terminal 6xHis tag. The molecular weight of this SETD5 protein is 30.4 kDa.

Aliases: SET Domain Containing 5, Histone-Lysine N-Methyltransferase SETD5, EC 2.1.1.43