RANBP2 Protein (AA 2553-2838)

Produktnummer ABIN7939501

Recombinant RANBP2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für RANBP2 Protein (AA 2553-2838) (ABIN7939501)

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 2553-2838

Verwendungszweck: Recombinant RANBP2 (2553-2838) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant RANBP2 (2553-2838) protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: RANBP2 (RAN Binding Protein 2 (RANBP2))

Andere Bezeichnung: RANBP2

Hintergrund:

Protein Background: RANBP2 (E3 SUMO-protein ligase RanBP2) is a E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1.

Short Description: Recombinant RANBP2 (2553-2838) protein that includes amino acids 2553-2838 of human RANBP2 protein (accession number NP_006258.3) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 34.05 kDa. The purity of the protein is ≥ 90 % by SDS-PAGE.

Aliases: E3 SUMO-protein ligase, RanBP2, NUP358, ADANE, ANE1, P270, TRP1

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus