PRDM4 Protein

Produktnummer ABIN7939442

Dieses Recombinant PRDM4-Protein wird in Baculovirus infected Insect Cells produziert.

Kurzübersicht für PRDM4 Protein (ABIN7939442)

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant PRDM4 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant PRDM4 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Andere Bezeichnung: PRDM4

Hintergrund:

Protein Background: PRDM4 (PR/SET Domain 4) is a transcription factor of the PR-domain protein family. It contains a PRdomain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. PRDM4 recruits the chromatin modifier PRMT5, an arginine methyltransferase that catalyzes symmetric dimethylation of histone H4 arginine 3 (H4R3me2s) to exerts histone methyltransferase activity. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). Diseases associated with PRDM4 include Pseudo-Von Willebrand Disease and Porokeratosis.

Short Description: Recombinant PRDM4 protein was expressed in baculovirus expression system as the full length protein (accession number NP_036538.3) with a N-terminal FLAG tag. The molecular weight of the protein is 89.2 kDa.

Aliases: PR/SET Domain 4

Pathways: Neurotrophin Signalübertragung