PDGFRB Protein (AA 557-1106)

Produktnummer ABIN7939425

Dieses Recombinant PDGFRB-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für PDGFRB Protein (AA 557-1106) (ABIN7939425)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 557-1106

Verwendungszweck: Recombinant PDGFRB (557-1106) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant PDGFRB (557-1106) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Andere Bezeichnung: PDGFRB

Hintergrund:

Protein Background: PDGFRB (Platelet Derived Growth Factor Receptor Beta), a tyrosine-protein kinase that acts as cell surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, PDGFRB plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration and plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. PDGFRB plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.

Short Description: Recombinant PDGFRB (557-1106) protein that includes amino acids 557-1106 of human PDGFRB protein (accession number NP_002600.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 63 kDa.

Aliases: Platelet Derived Growth Factor Receptor Beta

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling