N6AMT1 Protein

Produktnummer ABIN7939360

Recombinant N6AMT1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für N6AMT1 Protein (ABIN7939360)

Target: N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant N6AMT1 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant N6AMT1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol and 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))

Andere Bezeichnung: N6AMT1

Hintergrund:

Protein Background: DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women are unclear.N6AMT1(N-6 adenine-specific DNA methyltransferase 1) encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants.

Short Description: Recombinant N6AMT1 protein that includes full length of human N6AMT1 protein (accession number NP_037372.4) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 49.79 kDa.

Aliases: DNA N6-methyladenosine, N-6-Adenine-Specific DNA Methyltransferase 1, PRED28, KMT9, N6AMT, HEMK2, MTQ2, PRMC