MAP4K6 Protein (AA 1-320)

Produktnummer ABIN7939316

Recombinant MAP4K6-Protein exprimiert in Baculovirus infected Insect Cells.

Kurzübersicht für MAP4K6 Protein (AA 1-320) (ABIN7939316)

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 1-320

Verwendungszweck: Recombinant MINK1 (1-320) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Recombinant MINK1 (1-320) protein is supplied at a concentration of 0.25 μg/ul in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Andere Bezeichnung: MINK1

Hintergrund:

Protein Background: MINK1 (Misshapen Like Kinase 1) is a serine/threonine kinase which acts as a negative regulator of Rasrelated Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. MINK1 is required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. MINK1 can activate the JNK and MAPK14/p38 pathways and mediate stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Diseases associated with MINK1 include Alzheimer Disease 15 and Shipyard Eye.

Short Description: Recombinant MINK1 (1-320) protein that includes amino acids 1-320 of human MINK1 protein (accession number NP_722549.2) was expressed in a baculovirus expression system and contains an N-terminal FLAG tag. The molecular weight of the protein is 37.7 kDa.

Aliases: Misshapen Like Kinase 1

Pathways: Synaptic Membrane