GSG2 Protein (AA 470-798)

Produktnummer ABIN7938857

Recombinant GSG2-Protein exprimiert in Baculovirus infected Insect Cells.

Kurzübersicht für GSG2 Protein (AA 470-798) (ABIN7938857)

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 470-798

Verwendungszweck: Recombinant GSG2 (470-798) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant GSG2 (470-798) / HASPIN protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Andere Bezeichnung: GSG2

Hintergrund:

Protein Background: HASPIN (Histone H3 Associated Protein Kinase) is a serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. It may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

Short Description: Recombinant GSG2 (470-798) / HASPIN protein that includes amino acids 470-798 of human GSG2 protein (accession number NP_114171.2) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 38.7 kDa

Aliases: Histone H3 Associated Protein Kinase