FRK Protein (AA 208-505)

Produktnummer ABIN7938852

Dieses Recombinant FRK-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für FRK Protein (AA 208-505) (ABIN7938852)

Target: FRK (Fyn-Related Kinase (FRK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Produktdetails

Proteineigenschaft: AA 208-505

Verwendungszweck: Recombinant FRK (208-505) protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant FRK (208-505) protein is supplied in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: FRK (Fyn-Related Kinase (FRK))

Andere Bezeichnung: FRK

Hintergrund:

Protein Background: FRK is a non-receptor tyrosine-protein kinase that negatively regulates cell proliferation and positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth and may function as a tumor suppressor. Diseases associated with FRK include Co-Trimoxazole Allergy and Osseous Heteroplasia, Progressive.

Short Description: Recombinant FRK (208-505) protein that includes amino acids 208-505 of human FRK protein (accession number NP_002022.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 36.5 kDa

Aliases: Fyn-related kinase, Rak