EEF1A2 Protein

Produktnummer ABIN7938818

Recombinant EEF1A2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für EEF1A2 Protein (ABIN7938818)

Target: EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant EEF1A2 protein

Produktmerkmale: EEF1A2 (Eukaryotic Translation Elongation Factor 1 Alpha 2), also called as EF1A or Statin, is an isoform of the alpha subunit of the elongation factor-1 complex. This complex is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. There are two isoforms for subunit alpha, EEF1A1 and EEF1A2. EEF1A2 promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant EEF1A2 protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

Andere Bezeichnung: EEF1A2

Hintergrund:

Protein Background: EEF1A2 (Eukaryotic Translation Elongation Factor 1 Alpha 2), also called as EF1A or Statin, is an isoform of the alpha subunit of the elongation factor-1 complex. This complex is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. There are two isoforms for subunit alpha, EEF1A1 and EEF1A2. EEF1A2 promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.

Short Description: Recombinant EEF1A2 protein was expressed in E.coli as the full length protein (accession number NP_001949.1) with an N-terminal 6xHis Tag. The molecular weight of the protein is 54 kDa.

Aliases: Eukaryotic Translation Elongation Factor 1 Alpha 2