CHD7 Protein

Produktnummer ABIN7938717

Dieses Recombinant CHD7-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für CHD7 Protein (ABIN7938717)

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant CHD7 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant CHD7 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Andere Bezeichnung: CHD7

Hintergrund:

Protein Background: CHD7 is one of the nine members of the chromodomain helicase DNA-binding family of ATP-dependent chromatin remodeling enzymes. CHD proteins are broadly classified into three subfamilies on the basis of their constituent domains: subfamily I (CHD1 and CHD2), subfamily II (CHD3, CHD4 and CHD5) and sub-family III (CHD6, CHD7, CHD8 and CHD9). CHD7 is the most extensively studied member of CHD subfamily III. Mutations in CHD7 give rise to CHARGE syndrome, a human condition characterized by malformation of various organs.

Short Description: Recombinant CHD7 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_060250.2) with an N-terminal FLAG tag. The molecular weight of CHD7 is 337.2 kDa.

Aliases: CRG, KAL5, HH5, IS3, Chromodomain Helicase DNA binding protein 7

Pathways: Sensory Perception of Sound, Chromatin Binding