CHD3 Protein

Produktnummer ABIN7938712

Dieses Recombinant CHD3-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für CHD3 Protein (ABIN7938712)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant CHD3 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant CHD3 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Andere Bezeichnung: CHD3

Hintergrund:

Protein Background: CHD3 (Chromodomain Helicase DNA Binding Protein 3) is a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/ NuRD complex which participates in the remodeling of chromatin by deacetylating histones and is required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. Diseases associated with CHD3 include Snijders Blok-Campeau Syndrome and Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome.

Short Description: Recombinant CHD3 protein was expressed in baculovirus expression system as the full length protein (accession number NP_005843.2) with a N-terminal FLAG tag. The molecular weight of the protein is 224 kDa.

Aliases: Chromodomain helicase DNA binding protein 3