CTBP1 Protein

Produktnummer ABIN7938668

Recombinant CTBP1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für CTBP1 Protein (ABIN7938668)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant CTBP1 protein

Produktmerkmale: CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It is a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. It is involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex, and has functions in brown adipose tissue (BAT) differentiation.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant CTBP1 protein is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 10 % glycerol, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Andere Bezeichnung: CTBP1

Hintergrund:

Protein Background: CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It's a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.

Short Description: Recombinant CTBP1 protein was expressed in E.coli as the full length protein (accession number (NP_001319.1) with an N-terminal 6x-His Tag. The molecular weight of the protein is 51.1 kDa.

Aliases: C-terminal Binding Protein, BARS

Pathways: Retinoic Acid Receptor Signaling Pathway