IL-31 Protein (His tag)

Produktnummer ABIN7884497

Dieses Recombinant IL-31-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für IL-31 Protein (His tag) (ABIN7884497)

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB)

Reinheit: >98 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses IL-31 Protein ist gelabelt mit His tag.

Verwendungszweck: IL-31 (Interleukin-31), Mouse

Sequenz: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCF NPLNLNISVP GNTDESYDCK VFVLTVLKQF SNCMAELQAK DNTTC with polyhistid ine tag at the Cterminus

Endotoxin-Niveau: <0.1 EU per 1 μg protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: dissolve in sterile H2O

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Andere Bezeichnung: IL-31

Hintergrund: Interleukin-31 (IL-31) s an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. It is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

Molekulargewicht: 18kDa

Gen-ID: 76399

NCBI Accession: NP_083870

UniProt: Q6EAL8