DLL1 Protein (AA 18-723)

Produktnummer ABIN7866014

Recombinant DLL1-Protein exprimiert in CHO Cells.

Kurzübersicht für DLL1 Protein (AA 18-723) (ABIN7866014)

Target: DLL1 (delta-Like 1 (DLL1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: >95 % , as determined by SDS-PAGE and HPLC

Produktdetails

Proteineigenschaft: AA 18-723

Verwendungszweck: Human DLL1 Protein Recombinant

Sequenz: SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF

Produktmerkmale:

Protein Size: Recombinant DLL1 migrates as an approximately 57 kDa protein due to glycosylation under reducing conditions in SDS-PAGE.

Sequence Position: Optimized DNA sequence encoding Human DLL1 mature chain including a C-terminal 6xHis tag was expressed in CHO. Recombinant Human Delta-like protein 1 encodes amino acid residues 18-723.

Endotoxin-Niveau: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg(1EU/μg).

Biological Activity Comment: DLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 μg/ml

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Buffer: DLL1 was Lyophilized from PBS, pH 7.2.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this product can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 24 months

Antigendetails

Target: DLL1 (delta-Like 1 (DLL1))

Andere Bezeichnung: DLL1

Molekulargewicht: 57 kDa

Pathways: Notch Signalweg, Stem Cell Maintenance