WFDC2 Protein

Produktnummer ABIN7849738

Dieses Recombinant WFDC2-Protein wird in Yeast (Pichia pastoris) produziert.

Kurzübersicht für WFDC2 Protein (ABIN7849738)

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Yeast (Pichia pastoris)

Applikation: ELISA, SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human Epididymis Protein 4, HE4 Protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris-HCL ( pH 7.4±0.2) with 0.2 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Andere Bezeichnung: HE4

Hintergrund:

Synonyms: Human epididymis protein 4, HE4, WAP four-disulfide core domain protein 2, WFDC2

Description: Recombinant human HE4 protein.

Background: WAP four-disulfide core domain protein 2,also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs(epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types ofEOCs.