CKM Protein

Produktnummer ABIN7849674

Recombinant CKM-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für CKM Protein (ABIN7849674)

Target: CKM (Creatine Kinase, Muscle (CKM))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: ELISA

Reinheit: >90 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human Creatine kinase muscle,CK-MMprotein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 20 mM Tris-HCl pH 8.0.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: CKM (Creatine Kinase, Muscle (CKM))

Andere Bezeichnung: Creatine kinase muscle,CK-MM

Hintergrund:

Synonyms: CKM, CKMM, creatine kinase M, Creatine kinase M type, creatine kinase muscle, creatine kinase muscle type, Creatine Kinase M-type, M-CK, MCK.

Description: Recombinant creatine kinasemuscle type,CK-MM Protein.

Background: Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.