ICA1 Protein

Produktnummer ABIN7849664

Dieses Recombinant ICA1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für ICA1 Protein (ABIN7849664)

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: ELISA

Reinheit: >85 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human Islet cells Antigen,ICA69/ ICA1 Protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM Tris-HCl, 2mm EDTA with 0.1 % SKL as the preservative.

Konservierungsmittel: Other preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Ship at 4°C. Upon receipt, aliquot and store at -20°C or for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Andere Bezeichnung: ICA69 ICA1

Hintergrund:

Synonyms: 69 kDa islet cell autoantigen, Diabetes mellitus type I autoantigen, ICA 1, ICA1, ICA69, ICAp69, Islet cell autoantigen 1 (69kD), Islet cell autoantigen 1 69 kDa, Islet cell autoantigen 1, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69.

Description: Recombinant human Islet cells Antigen 69 protein with molecular weight of 72 kDa.

Background: Islet cell autoantigen 1 is a protein that in humans is encoded by the ICA1 gene.This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.