AMH Protein

Produktnummer ABIN7849648

Dieses Recombinant AMH-Protein wird in HEK-293F Cells produziert.

Kurzübersicht für AMH Protein (ABIN7849648)

Target: AMH (Anti-Mullerian Hormone (AMH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293F Cells

Applikation: SDS-PAGE (SDS), ELISA

Reinheit: >95 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human Muellerian-inhibiting substance/Anti-Muellerian hormone, MIS/AMH Protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS ( pH 7.4).

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: AMH (Anti-Mullerian Hormone (AMH))

Andere Bezeichnung: MISAMH

Hintergrund:

Synonyms: Muellerian-inhibiting factor, MIF, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS

Description: Recombinant human AMH protein from the region of N-terminal.

Background: Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH is a standard marker of ovarian reserve. Correlation between AMH and egg euploidy is controversial. Gat I et al study shows a correlation between AMH and aneuploidy rate, specifically among infertile patients younger than 37 years old. AMH is also a reliable marker of ovarian reserve in endometriosis patients, and it can predict follicular density in women undergoing ovarian tissue cryopreservation. In mammals, AMH prevents the development of the Müllerian ducts into the uterus and other Müllerian structures. The effect is ipsilateral, that is each testis suppresses Müllerian development only on its own side. In humans, this action takes place during the first 8 weeks of gestation. If no hormone is produced from the gonads, the Müllerian ducts automatically develop, while the Wolffian ducts, which are responsible for male reproductive parts, automatically die.

Pathways: Negative Regulation of Hormone Secretion