Transferrin Protein (TF) (Holo)

Produktnummer ABIN7833114

Recombinant Transferrin-Protein exprimiert in HEK 293 Cells.

Kurzübersicht für Transferrin Protein (TF) (Holo) (ABIN7833114)

Target: Transferrin (TF)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK 293 Cells

Applikation: Cell Culture (CC)

Reinheit: More than 98% by SDS-PAGE

Güteklasse: Animal-Free

Produktdetails

Proteineigenschaft: Holo

Verwendungszweck: Human holo-Transferrin (Animal free) protein

Sequenz: AA 679

Biological Activity Comment: The biological activity is determined by the stimulation of cell proliferation of MDCK cells in serum-free cell culture medium.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial prior to opening. Do not vortex. The lyophilized HTF should be reconstituted in water to a concentration of 1.0 mg/mL.

Buffer: PBS (pH 7.4)

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: The lyophilized HTF is stable at room temperature for 1 month and at 2 °C to 8 °C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

Haltbarkeit: 6 months

Antigendetails

Target: Transferrin (TF)

Andere Bezeichnung: Transferrin

Hintergrund: Description: Transferrin (TF) is found in vertebrate that mediates the transport of iron through blood plasma. When not bound to iron, the protein is known as apo-Transferrin. Each molecule contains two binding sites for iron in the ferric form Fe(III). The iron-bound holo-Transferrin (HTF) can bind to the dimeric Transferrin receptor (TfR) on a cell’s surface and is subsequently internalized by endocytosis. A reduction of pH in the vesicle decreases its iron-affinity and causes HTF to release bound iron ions. Transferrin appears to be essential for most cells growing in tissue culture. ReliaTech's Recombinant Human holo-Transferrin is a 76 kDa glycoprotein consisting of 679 amino acid residues.
Synonyms: HTF, Serotransferrin, Transferrin, TF, Holo Transferrin, Beta-1 metal-binding-globulin, Siderophilin

Molekulargewicht: 76 kDa

NCBI Accession: NP_001054

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis