CXCR2 Protein (AA 1-45) (Fc Tag)

Produktnummer ABIN7829762

Dieses Recombinant CXCR2-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CXCR2 Protein (AA 1-45) (Fc Tag) (ABIN7829762)

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Applikation: Screening Assay (ScA), Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA)

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Proteineigenschaft: AA 1-45

Aufreinigungstag / Konjugat: Dieses CXCR2 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Mouse CXCR2 Protein with C-terminal human Fc tag

Spezifität: Mouse CXCR2(Met1-Ile45) hFc(Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Anwendungsinformationen

Applikationshinweise: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Kommentare:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Andere Bezeichnung: CXCR2

Hintergrund: CD128, IL8RA, Il8rb, CDw128, Cmkar2, Gpcr16, IL-8Rh, IL-8rb, mIL-8RH
Enables chemokine receptor activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be located in several cellular components, including cell surface, mast cell granule, and mitotic spindle. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system, central nervous system, embryo mesenchyme, epithelium, and heart. Human ortholog(s) of this gene implicated in IgA glomerulonephritis, WHIM syndrome 2, acute pyelonephritis, end stage renal disease, and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2). [provided by Alliance of Genome Resources, May 2025]

Molekulargewicht: predicted molecular mass of 31.2 kDa after removal of the signal peptide.

UniProt: P35343

Pathways: cAMP Metabolic Process