VEGF (Aflibercept Biosimilar) Protein (Fc Tag)

Produktnummer ABIN7795087

Dieses Recombinant VEGF (Aflibercept Biosimilar)-Protein wird in CHO Cells exprimiert.

Kurzübersicht für VEGF (Aflibercept Biosimilar) Protein (Fc Tag) (ABIN7795087)

Target: VEGF (Aflibercept Biosimilar)

Protein-Typ: Recombinant

Spezies: Human

Quelle: CHO Cells

Applikation: In vivo Studies (in vivo)

Reinheit: >95% by SDS-PAGE under reducing conditions and HPLC

Güteklasse: Research Grade

Produktdetails

Aufreinigungstag / Konjugat: Dieses VEGF (Aflibercept Biosimilar) Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (hIgG1).

Spezifität: The aflibercept biosimilar protein specifically binds to the human VEGF.

Produktmerkmale: Research grade Aflibercept biosimilar has the same amino acid sequence as Aflibercept (trade name Eylea), a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (IgG1). It inhibits vascular endothelial growth factor (VEGF), and is used in the treatment of macular edema following Central Retinal Vein Occlusion (CRVO) and neovascular Age-Related Macular Degeneration (AMD). Aflibercept is a dimeric glycoprotein with a molecular weight of 96.9 kilo Daltons (kDa). Glycosylation adds its molecular weight to 115 kDa in total. Ziv-aflibercept (trade name Zaltrap) was developed as an injection for treatment of metastatic colorectal cancer.

Aufreinigung: The aflibercept biosimilar protein was produced in CHO stable cell line.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Anwendungsinformationen

Applikationshinweise: Functional assays, and those assays for studying biological pathways affected by aflibercept.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: pH 6.1, no stabilizers or preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Haltbarkeit: 12 months

Antigendetails

Target: VEGF (Aflibercept Biosimilar)

Andere Bezeichnung: Aflibercept Biosimilar

Substanzklasse: Biosimilar