PODXL Protein (SUMO-His Tag)

Produktnummer ABIN7669448

Dieses Recombinant PODXL-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für PODXL Protein (SUMO-His Tag) (ABIN7669448)

Target: PODXL (Podocalyxin-Like (PODXL))

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses PODXL Protein ist gelabelt mit SUMO-His Tag.

Verwendungszweck: Recombinant Human PODXL protein (SUMO,His tag)

Sequenz: Ala 220-Ile 431

Aufreinigung: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: PODXL

Hintergrund: Podocalyxin (PODXL), also known as Podocalyxin-like protein 1 (PCLP-1), is a heavily glycosylated transmembrane sialoprotein in the CD34 and Endoglycan family.Podocalyxin is expressed on glomerular and vascular endothelial cells, neurons, hematopoietic, mesenchymal, and cardiac stem cells, and metastatic carcinoma and glioblastoma tumor cells. A soluble form of Podocalyxin can be released into the urine of women with pre-eclampsia. Podocalyxin promotes platelet activation, neurite outgrowth, branching, and synaptogenesis, homing of hematopoietic progenitor cells to the bone marrow and spleen, and engraftment of mesenchymal and cardiac stem cells into ischemic heart and kidney. Its interactions with L-Selectin and E-Selectin mediate the tethering of lymphocytes and metastatic tumor cells to the vascular endothelium.,PCLP,PCLP-1,PCLP1,PCLPGCTM-2 antigen,PCpodocalyxin,POD XL,PODXL,Podocalyxin,Podocalyxin-like protein 1,podocalyxin-like

Molekulargewicht:

calculated_mw: 34.2 kDa

observed_mw: 32 kDa

UniProt: O00592

Pathways: Tube Formation