Nectin-4 (NECTIN4) (Inactive) protein (His tag)

Produktnummer ABIN7669348

Dieses Recombinant -Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Nectin-4 (NECTIN4) (Inactive) protein (His tag) (ABIN7669348)

Target: Nectin-4 (NECTIN4)

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Recombinant Human Nectin-4/NECTIN4 protein (His tag)

Sequenz: Gly 32-Leu 146

Aufreinigung: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Nectin-4 (NECTIN4)

Andere Bezeichnung: Nectin-4,NECTIN4

Hintergrund: Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and-heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.,Ig superfamily receptor LNIR,LNIR,Nectin-4,PRR4,PVRL4,Poliovirus receptor-related protein 4

Molekulargewicht:

calculated_mw: 12.5 kDa

observed_mw: 15 kDa

UniProt: Q96NY8