Cofilin 2 Protein (CFL2) (His tag)

Produktnummer ABIN7668552

Recombinant Cofilin 2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Cofilin 2 Protein (CFL2) (His tag) (ABIN7668552)

Target: Cofilin 2 (CFL2)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Cofilin 2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CFL2/cofilin 2/ADF Protein (His Tag)

Sequenz: Ala 2-Leu 166

Aufreinigung: > 98 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Cofilin 2 (CFL2)

Andere Bezeichnung: CFL2

Hintergrund: NEM7,Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH -dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.

Molekulargewicht:

Calculated MW: 20.4 kDa

Observed MW: 21 kDa

Gen-ID: 1073

UniProt: Q9Y281

Pathways: Caspase Kaskade in der Apoptose