CBLC Protein (His-GST)

Produktnummer ABIN7668326

Dieses Recombinant CBLC-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für CBLC Protein (His-GST) (ABIN7668326)

Target: CBLC (Cbl proto-oncogene C (CBLC))

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses CBLC Protein ist gelabelt mit His-GST.

Verwendungszweck: Recombinant Human Cbl-c/CBL-3 Protein (His & GST Tag)

Sequenz: Met 1-Ala474

Aufreinigung: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM Nacl, 10 % glycerol, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CBLC (Cbl proto-oncogene C (CBLC))

Andere Bezeichnung: Cbl-c

Hintergrund: CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.,CBL-3,CBL-SL,RNF57

Molekulargewicht:

calculated_mw: 80.2 kDa

observed_mw: 66 kDa

UniProt: Q9ULV8

Pathways: EGFR Signaling Pathway