CCR3 Protein

Produktnummer ABIN7597219

Dieses MNP Membrane Nanoparticle CCR3-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CCR3 Protein (ABIN7597219)

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Protein-Typ: MNP Membrane Nanoparticle

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Verwendungszweck: Human CCR3 full length protein-MNP

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Andere Bezeichnung: CCR3

Hintergrund: CC-CKR-3, C C CKR3, CD193, CKR 3, CKR3, CMKBR3
The protein is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

Molekulargewicht: The human full length CCR3 protein has a MW of 41.0 kDa

UniProt: P51677