CCR7 Protein

Produktnummer ABIN7597218

MNP Membrane Nanoparticle CCR7-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für CCR7 Protein (ABIN7597218)

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Protein-Typ: MNP Membrane Nanoparticle

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Verwendungszweck: Human CCR7 full length protein-MNP

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Andere Bezeichnung: CCR7

Hintergrund: BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
The protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis.

Molekulargewicht: The human full length CCR7 protein has a MW of 42.9 kDa

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process