SREBF chaperone Protein (SCAP) (DYKDDDDK Tag)

Produktnummer ABIN7596504

Synthetic Nanodisc SREBF chaperone-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für SREBF chaperone Protein (SCAP) (DYKDDDDK Tag) (ABIN7596504)

Target: SREBF chaperone (SCAP)

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Applikation: ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)

Produktdetails

Aufreinigungstag / Konjugat: Dieses SREBF chaperone Protein ist gelabelt mit DYKDDDDK Tag.

Verwendungszweck: Human SCAP full length protein-synthetic nanodisc

Anwendungsinformationen

Kommentare:

Advantages:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins
• Mammalian cell expression system ensures post- translational modifications

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: SREBF chaperone (SCAP)

Andere Bezeichnung: SCAP

Hintergrund: N/A
A protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Molekulargewicht: The human full length SCAP protein has a MW of 139.7 kDa

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interaktom