IL23 Protein (His tag)

Produktnummer ABIN7596392

Dieses Recombinant IL23-Protein wird in Baculovirus infected Insect Cells exprimiert.

Kurzübersicht für IL23 Protein (His tag) (ABIN7596392)

Target: IL23 (Interleukin 23 (IL23))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: SDS-PAGE (SDS)

Reinheit: > 95% by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses IL23 Protein ist gelabelt mit His tag.

Sequenz: IL12B(p40),IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS,IL23A(p19),RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: IL23 (Interleukin 23 (IL23))

Andere Bezeichnung: IL-23

Hintergrund: IL23 p40 and p19, also known as interleukin-12 subunit beta/interleukin-23 subunit alpha, is a heterodimeric cytokine composed of two disulfide-linked subunit, a p19 subunit that is unique to IL23, and a p40 subunit that is shared with IL12. The p19 subunit has homology to the p35 subunit of IL12, as well as to other single chain sytokines sub as IL6 and IL11. It is produced by macrophages and B lymphocytes and has multiple effects on T-cells and NK cells, including stimulation of cytotoxic activity, proliferation, and promotion of Th1 development as well as IFN-gamma and TNF production. Recombinant human IL23 p40 and p19, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 34.6 kDa (p40, 306aa),19.5 kDa (p19, 176aa)