CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag)
Kurzübersicht für CD9 Protein (CD9) (AA 112-195) (hIgG-His-tag) (ABIN7596342)
Target
Alle CD9 Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 112-195
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Aufreinigungstag / Konjugat
- Dieses CD9 Protein ist gelabelt mit hIgG-His-tag.
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Sequenz
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SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI -
Endotoxin-Niveau
- < 1 EU per 1ug of protein (determined by LAL method)
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD9
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Andere Bezeichnung
- CD9
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Hintergrund
- CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molekulargewicht
- 36.9kDa (326aa)
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NCBI Accession
- NP_001760
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Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
Target
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