MitTx Toxin (Active) Protein

Produktnummer ABIN7887288

Native MitTx Toxin-Protein exprimiert in Micrurus tener tener (Texas coral snake).

Kurzübersicht für MitTx Toxin (Active) Protein (ABIN7887288)

Target: MitTx Toxin

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Micrurus tener tener

Quelle: Micrurus tener tener (Texas coral snake)

Reinheit: ≥98 % (HPLC)

Produktdetails

Verwendungszweck: MitTx Toxin

Sequenz: MitTx-α subunit:
QIRPAFCYED PPFFQKCGAF VDSYYFNRSR ITCVHFFYGQ CDVNQNHFTT MSECNRVCHG
MitTx-β subunit:
NLNQFRLMIK CTNDRVWADF VDYGCYCVAR DSNTPVDDLD RCCQAQKQCY DEAVKVHGCK PLVMFYSFEC RYLASDLDCS GNNTKCRNFV CNCDRTATLC ILTATYNRNN HKIDPSRCQ

Spezifität: Toxin target: ASIC1-containing acid-sensing ion channels (ASICs) 

Biological Activity Comment: MitTx toxin activates ASIC1-containing channels1,2.

Anwendungsinformationen

Applikationshinweise: Antigen Preadsorption Control: 20 nM

Kommentare:

Electrophysiology

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1  mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

Buffer: Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).

Handhabung: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

Lagerung: -20 °C

Informationen zur Lagerung: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Antigendetails

Target: MitTx Toxin

Hintergrund: An activator of ASIC1-containing channels

Molekulargewicht: 20.84 kDa (i± subunit, 7.104 kDa and i² subunit, 13.736 kDa)

UniProt: G9I930, G9I929