alpha-Latrotoxin (Active) Protein

Produktnummer ABIN7887287

Dieses Native alpha-Latrotoxin-Protein wird in Latrodectus tredecimguttatus (Mediterranean black widow spider) exprimiert.

Kurzübersicht für alpha-Latrotoxin (Active) Protein (ABIN7887287)

Target: alpha-Latrotoxin

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Latrodectus tredecimguttatus

Quelle: Latrodectus tredecimguttatus (Mediterranean black widow spider)

Reinheit: ≥97 %

Produktdetails

Verwendungszweck: α-Latrotoxin

Spezifität: Toxin target: Neurexin-1, ADGRL1 (latrophilin-1/CIRL), and tyrosine-protein phosphatase S (PTPRS) receptors

Biological Activity Comment: α-Latrotoxin induces exhaustive neurotransmitter release from nerve terminals1. Indirectly activates the ERK MAP kinase pathway.

Anwendungsinformationen

Applikationshinweise: Antigen Preadsorption Control: 150 pM - 1 nM

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Carefully add the solvent directly to the vial interior. Dissolve the material by gently tapping, tilting, or rolling the vial. Avoid vigorous shaking or vortexing Reconstitute in high-quality pure water or a conventional buffer (e.g., 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.1 mM CaCl₂, and 0.2 mM MgCl₂). Avoid multiple freeze-thaw cycles and maintain optimal biological activity.

Buffer: Lyophilized from 20 mM KPO4 buffer, pH 6.8.

Handhabung: Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. protect from moisture

Lagerung: -20 °C

Informationen zur Lagerung: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.

Antigendetails

Target: alpha-Latrotoxin

Hintergrund: A potent inducer of massive neurotransmitter release via presynaptic neurexin and latrophilin receptors

Molekulargewicht: 130 kDa

UniProt: P23631

CAS-Nummer: 65988-34-3