ICAM1 Protein (AA 28-485) (Fc Tag)
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- Target Alle ICAM1 Proteine anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 28-485
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Spezies
- Maus
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Quelle
- CHO Cells
- Aufreinigungstag / Konjugat
- Dieses ICAM1 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)
- Kreuzreaktivität
- Maus
- Produktmerkmale
- The extracellular domain of mouse CD54 [ICAM-1] (aa 28-485) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
- Reinheit
- >98 % (SDS-PAGE)
- Sterilität
- Sterile filtered
- Endotoxin-Niveau
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Top Product
- Discover our top product ICAM1 Protein
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Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-480) protein (His tag)
ICAM1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-480) protein (His tag)ICAM1 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-485) protein (His tag)ICAM1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Intercellular Adhesion Molecule 1 (ICAM1) (AA 48-480) protein (mFc Tag)ICAM1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-480) (Active) protein (Fc Tag)ICAM1 Spezies: Human Wirt: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
Intercellular Adhesion Molecule 1 (ICAM1) (AA 26-272) protein (His-IF2DI Tag)ICAM1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-532) protein (GST tag)ICAM1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag)ICAM1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag,Fc Tag)ICAM1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag)ICAM1 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Handhabung
- Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- CD54 [ICAM-1] (ICAM1 Produkte)
- Hintergrund
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ICAM1, Intercellular Adhesion Molecule 1
Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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