RGS3 Protein (AA 1-966) (His tag)

Produktnummer ABIN7565013

Recombinant RGS3-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für RGS3 Protein (AA 1-966) (His tag) (ABIN7565013)

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-966

Aufreinigungstag / Konjugat: Dieses RGS3 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Rgs3 Protein expressed in mammalian cells.

Sequenz: MNRFNGLCKV CSERRYRQIT IRRGKDGFGF TICCDSPVRV QAVDSGGPAE RAGLQQLDTV LQLNERPVEH WKCVELAHEI RSCPSEIILL VWRVVPQIKP GPDGGVLRRA SCKSTHDLLS PPNKREKNCT HGAPVRPEQR HSCHLVCDSS DGLLLGGWER YTEVGKRSGQ HTLPALSRTT TPTDPNYIIL APLNPGSQLL RPVYQEDTIP EEPGTTTKGK SYTGLGKKSR LMKTVQTMKG HSNYQDCSAL RPHIPHSSYG TYVTLAPKVL VFPVFVQPLD LCNPARTLLL SEELLLYEGR NKTSQVTLFA YSDLLLFTKE EEPGRCDVLR NPLYLQSVKL QEGSSEDLKF CVLYLAEKAE CLFTLEAHSQ EQKKRVCWCL SENIAKQQQL AAPPTERKMF ETEADEKEMP LVEGKGPGAE EPAPSKNPSP GQELPPGQDL PPSKDPSPSQ ELPAGQDLPP SKDPSPSQEL PAGQDLPPSK DPSPSQELPV GQDLPPRKDS SGQEAAPGPE SPSSEDIATC PKPPQSPETS TSKDSPPGQG SSPTTELPSC QGLPAGQEST SQDPLLSQEP PVIPESSASV QKRLPSQESP SSLGSLPEKD LAEQTISSGE PPVATGAVLP ASRPNFVIPE VRLDNAYSQL DGAHGGSSGE DEDAEEGEEG GEGEEDEEDD TSDDNYGDRS EAKRSSLIET GQGAEGGFSL RVQNSLRRRT HSEGSLLQES RGPCFASDTT LHCSDGEGAT STWAIPSPRT LKKELGRNGG SMHHLSLFFT GHRKMSGTDL TECDEASRKR KSKNIAKDMK NKLAIFRRRN ESPGAQPASK TDKTTKSFKP TSEEALKWSE SLEKLLLHKY GLEVFQAFLR TEFSEENLEF WLACEDFKKV KSQSKMAAKA KKIFAEFIAI QACKEVNLDS YTREHTKENL QSITRGCFDL AQKRIFGLME KDSYPRFLRS DLYLDLINQK KMSPPL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Andere Bezeichnung: Rgs3

Hintergrund: Regulator of G-protein signaling 3 (RGS3) (C2PA),FUNCTION: Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:11301003, ECO:0000269|PubMed:12210723}.

Molekulargewicht: 106.2 kDa

UniProt: Q9DC04

AlphaFold: Q9DC04

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling