ARPIN Protein (AA 1-226) (His tag)

Produktnummer ABIN7560823

Dieses Recombinant ARPIN-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für ARPIN Protein (AA 1-226) (His tag) (ABIN7560823)

Target: ARPIN

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-226

Aufreinigungstag / Konjugat: Dieses ARPIN Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Arpin Protein expressed in mammalian cells.

Sequenz: MSRIYQDSAL RNKAVQSARL PGTWDPATHQ GGNGILLEGE LVDVSRHSIL DAHGRKERYY VLYIQPSCIH RRKFDPKGNE IEPNFSATRK VNTGFLMSSY KVEAKGDTDR LTLEALKSLV NKPQLLELTE SLTPDQAVAF WMPESEMEVM ELELGTGVRL KTRGDGPFID SLAKLELGTV TKCNFAGDGK TGASWTDNIM AQKSSERNTA EIREQGDGAE DEEWDD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: ARPIN

Hintergrund: Arpin (Arp2/3 inhibition protein),FUNCTION: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competitive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence (By similarity). {ECO:0000250}.

Molekulargewicht: 25.2 kDa

UniProt: Q9D0A3

AlphaFold: Q9D0A3