KLHL17 Protein (AA 1-640) (His tag)

Produktnummer ABIN7558111

Dieses Recombinant KLHL17-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für KLHL17 Protein (AA 1-640) (His tag) (ABIN7558111)

Target: KLHL17 (Kelch-Like 17 (KLHL17))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-640

Aufreinigungstag / Konjugat: Dieses KLHL17 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant Klhl17 Protein expressed in mammalian cells.

Sequenz: MQPRGERPAG RTQSPEHSSP GPGPEAPPPP QPPAPEAERA RPRQARPAAP MEGAMQLLSR EGHSVAHNSK RHYHDAFVAM SRMRQRGLLC DIVLHVAAKE IRAHKVVLAS CSPYFHAMFT NEMSESRQTH VTLHDIDPQA LDQLVQFAYT AEIVVGEGNV QTLLPAASLL QLNGVRDACC KFLLSQLDPS NCLGIRGFAD THSCSDLLKA AHRYVLQHFV DVAKTEEFML LPLKQVLELV SSDSLNVPSE EDVYRAVLSW VKHDVDTRRQ HVPRLMKCVR LPLLSRDFLL GHVDAESLVR HHPDCKDLLI EALKFHLLPE QRGVLGTSRT RPRRCEGAGP VLFAVGGGSL FAIHGDCEAY DTRTDRWHVV ASMSTRRARV GVAAVGNRLY AVGGYDGTSD LATVESYDPV TNTWQPEVSM GTRRSCLGVA ALHGLLYAAG GYDGASCLNS AERYDPLTGT WTSIAAMSTR RRYVRVATLD GNLYAVGGYD SSSHLATVEK YEPQVNSWTP VASMLSRRSS AGVAVLEGAL YVAGGNDGTS CLNSVERYST KAGAWESVAP MNIRRSTHDL VAMDGWLYAV GGNDGSSSLN SIEKYNPRTN KWVAASCMFT RRSSVGVAVL ELLNFPPPSS PTLSVSSTSL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: KLHL17 (Kelch-Like 17 (KLHL17))

Andere Bezeichnung: Klhl17

Hintergrund: Kelch-like protein 17 (Actinfilin),FUNCTION: Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes. The BCR(KLHL17) complex mediates the ubiquitination and subsequent degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). {ECO:0000250}.

Molekulargewicht: 69.7 kDa

UniProt: Q6TDP3

AlphaFold: Q6TDP3

Pathways: Synaptic Membrane