PAQR6 Protein (AA 1-344) (His tag)

Produktnummer ABIN7550551

Dieses Recombinant PAQR6-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für PAQR6 Protein (AA 1-344) (His tag) (ABIN7550551)

Target: PAQR6 (Progestin and AdipoQ Receptor Family Member VI (PAQR6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Produktdetails

Proteineigenschaft: AA 1-344

Aufreinigungstag / Konjugat: Dieses PAQR6 Protein ist gelabelt mit His tag.

Verwendungszweck: Predefined custom protein recombinant PAQR6 Protein expressed in mammalian cells.

Sequenz: MLSLKLPQLL QVHQVPRVFW EDGIMSGYRR PTSSALDCVL SSFQMTNETV NIWTHFLPTW YFLWRLLALA GGPGFRAEPY HWPLLVFLLP ACLYPFASCC AHTFSSMSPR MRHICYFLDY GALSLYSLGC AFPYAAYSMP ASWLHGHLHQ FFVPAAALNS FLCTGLSCYS RFLELESPGL SKVLRTGAFA YPFLFDNLPL FYRLGLCWGR GHGCGQEALS TSHGYHLFCA LLTGFLFASH LPERLAPGRF DYIGHSHQLF HICAVLGTHF QLEAVLADMG SRRAWLATQE PALGLAGTVA TLVLAAAGNL LIIAAFTATL LRAPSTCPLL QGGPLEGGTQ AKQQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: PAQR6 (Progestin and AdipoQ Receptor Family Member VI (PAQR6))

Andere Bezeichnung: PAQR6

Hintergrund: Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6),FUNCTION: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870). {ECO:0000269|PubMed:23161870, ECO:0000303|PubMed:23763432}.

Molekulargewicht: 38.0 kDa

UniProt: Q6TCH4

AlphaFold: Q6TCH4