DCST1 Protein (AA 1-706) (His tag)

Produktnummer ABIN7546993

Produktdetails

Target: DCST1 (DC-STAMP Domain Containing 1 (DCST1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-706

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DCST1 Protein ist gelabelt mit His tag.

Verwendungszweck: Custom-made recombinant DCST1 Protein expressed in mammalian cells.

Sequenz: MDIKHHQNGT RGQRRKQPHT TVQRLLTWGL PVSCSWFLWR QPGEFPVTAL LLGAGAGGLL AIGLFQLLVN PMNIYEEQKI MFLYSLVGLG AMGWGTSPHI RCASLLLVPK MLGKEGRLFV LGYALAAIYV GPVANLRHNL NNVIASLGCT VELQINNTRA AWRISTAPLR AMFKDLLSSK ELLRAETRNI SATFEDLDAQ VNSETGYTPE DTMDSGETAQ GREARQAPAS RLHLSTQKMY ELKTKLRCSY VVNQAILSCR RWFDRKHEQC MKHIWVPLLT HLLCLPMKFK FFCGIAKVME VWCRNRIPVE GNFGQTYDSL NQSIRGLDGE FSANIDFKEE KQAGVLGLNT SWERVSTEVR DYVYRQEARL EWALGLLHVL LSCTFLLVLH ASFSYMDSYN HDIRFDNIYI STYFCQIDDR RKKLGKRTLL PLRKAEEKTV IFPCKPTIQA SEMSNVVREL LETLPILLLL VVLCGLDWAL YSIFDTIRHH SFLQYSFRSS HKLEVKVGGD SMLARLLRKT IGALNTSSET VMESNNMPCL PQPVGLDARA YWRAAVPIGL LVCLCLLQAF GYRLRRVIAA FYFPKREKKR ILFLYNDLLK KRAAFTKLRR AAILRRERQQ KAPRHPLADI LHRGCPLLRR WLCRRCVVCQ APETPESYVC RTLDCEAVYC WSCWDDMRQR CPVCTPREEL SSSAFSDSND DTAYAG Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: DCST1 (DC-STAMP Domain Containing 1 (DCST1))

Andere Bezeichnung: DCST1 (DCST1 Produkte)

Hintergrund: E3 ubiquitin-protein ligase DCST1 (EC 2.3.2.27) (DC-STAMP domain-containing protein 1) (RING-type E3 ubiquitin transferase),FUNCTION: E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteasomal degradation thereby negatively regulating type-I-interferon signaling. Essential sperm cell-surface protein required for sperm-egg fusion and fertilization (By similarity). {ECO:0000250|UniProtKB:Q059Y8, ECO:0000269|PubMed:27782195}.

Molekulargewicht: 80.7 kDa

UniProt: Q5T197