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SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein Protein

cVLP -Protein exprimiert in HEK-293 Cells.
Produktnummer ABIN7538794

Kurzübersicht für SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein Protein (ABIN7538794)

Target

SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein

Protein-Typ

cVLP

Spezies

SARS Coronavirus-2 (SARS-CoV-2)

Quelle

  • 1
HEK-293 Cells

Applikation

ELISA, Nanoparticle Tracking Analysis (NTA), Western Blotting (WB)
  • Verwendungszweck

    Chimeric VLP of SARS-CoV-2 (M+E+N) can be used as a control

    Produktmerkmale

    Chimeric SARS-CoV-2 virus-like particles (cVLP) were produced in HEK cells by co-expression of the membrane-, envelope- and nucleoprotein with a membrane bound target protein. The VLPs do not contain the viral genome, cannot replicate and are not infectious.

    Aufreinigung

    Polyethylene glycol precipitation

    Biological Activity Comment

    active
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  • Applikationshinweise

    Applications: Immunogenic antigen, antigen for ELISA and Western blot.
    Western blot: 1-10 μg, ELISA: 1-5 μg/mL

    Kommentare

    Virus-like Particles are multiprotein complexes that resemble a native virus, but lack the genetic information. Therefore, VLPs are safe to handle in numerous fields of applications. For example, VLPs can be applied as antigen in serological assays (e.g. ELISA), or serve as reference material to standardize the performance of different diagnostic tests (e.g. rapid antigen tests or ELISA). Due to the self-adjuvanting properties of VLPs is the most common application of VLPs the use as antigen for immunizations for vaccine development or antibody discovery campaigns.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS

    Lagerung

    -80 °C

    Informationen zur Lagerung

    - 80°C
  • Target

    SARS-CoV-2 Membrane-, Envelope-, Nucleoprotein

    Hintergrund

    SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a coronavirus (genus: Betacoronavirus, subgenus: Sarbecovirus) that was identified as the cause of COVID-19 disease in early 2020.
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