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GPR17 Protein

This anti-GPR17 antibody (ABIN7538260) is a Mammalian Cells antibody detecting GPR17 in . Suitable for Human.
Produktnummer ABIN7538260

Kurzübersicht für GPR17 Protein (ABIN7538260)

Target

Alle GPR17 Proteine anzeigen
GPR17 (G Protein-Coupled Receptor 17 (GPR17))

Protein-Typ

Synthetic Nanodisc

Spezies

  • 7
  • 2
Human

Quelle

  • 3
  • 2
  • 2
  • 2
Mammalian Cells
  • Verwendungszweck

    Human GPR17 full length protein-synthetic nanodisc

    Produktmerkmale

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 16.256,82 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

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  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    GPR17 (G Protein-Coupled Receptor 17 (GPR17))

    Andere Bezeichnung

    GPR17

    Hintergrund

    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.[UniProtKB/Swiss-Prot Function]

    Molekulargewicht

    The human full length GPR17 protein has a MW of 41kDa

    UniProt

    Q13304
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