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BRS3 Protein

Dieses Synthetic Nanodisc BRS3-Protein wird in Mammalian Cells exprimiert.
Produktnummer ABIN7538145

Kurzübersicht für BRS3 Protein (ABIN7538145)

Target

Alle BRS3 Proteine anzeigen
BRS3 (Bombesin-Like Receptor 3 (BRS3))

Protein-Typ

Synthetic Nanodisc

Spezies

  • 3
  • 2
Human

Quelle

  • 3
  • 2
Mammalian Cells
  • Verwendungszweck

    Human BRS3 full length protein-synthetic nanodisc

    Produktmerkmale

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 16.256,82 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

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  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    BRS3 (Bombesin-Like Receptor 3 (BRS3))

    Andere Bezeichnung

    BRS3

    Hintergrund

    The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]

    Molekulargewicht

    The human full length BRS3 protein has a MW of 44.4kDa

    UniProt

    P32247

    Pathways

    Feeding Behaviour
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