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ADGRE5 (AA 21-552) protein (His tag)

Dieses Recombinant -Protein wird in Mammalian Cells produziert.
Produktnummer ABIN7538123

Kurzübersicht für ADGRE5 (AA 21-552) protein (His tag) (ABIN7538123)

Target

ADGRE5

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 2
Mammalian Cells

Reinheit

The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • Proteineigenschaft

    AA 21-552

    Aufreinigungstag / Konjugat

    His tag

    Verwendungszweck

    Recombinant human ADGRE5 Protein with C-terminal 6xHis tag

    Spezifität

    ADGRE5 (Gln21-Arg552) 6xHis tag

    Produktmerkmale

    Extracellular Domain Protein

    Aufreinigung

    Purified from cell culture supernatant by affinity chromatography
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    ADGRE5

    Hintergrund

    This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]

    Molekulargewicht

    predicted molecular mass of 58.9 kDa after removal of the signal peptide.

    UniProt

    P48960
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