Nectin-2 Protein (NECTIN2) (His tag)

Produktnummer ABIN7535985

Dieses Recombinant Nectin-2-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Nectin-2 Protein (NECTIN2) (His tag) (ABIN7535985)

Target: Nectin-2 (NECTIN2)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % by SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Nectin-2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Nectin-2/PVRL2/CD112 Protein

Sequenz: QDVRVRVLPE VRGRLGGTVE LPCHLLPPTT ERVSQVTWQR LDGTVVAAFH PSFGVDFPNS QFSKDRLSFV RARPETNADL RDATLAFRGL RVEDEGNYTC EFATFPNGTR RGVTWLRVIA QPENHAEAQE VTIGPQSVAV ARCVSTGGRP PARITWISSL GGEAKDTQEP GIQAGTVTII SRYSLVPVGR ADGVKVTCRV EHESFEEPIL LPVTLSVRYP PEVSISGYDD NWYLGRSEAI LTCDVRSNPE PTDYDWSTTS GVFPASAVAQ GSQLLVHSVD RMVNTTFICT ATNAVGTGRA EQVILVRESP STAGAGATGG

Spezifität: Gln32-Gly351

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: Nectin-2 (NECTIN2)

Andere Bezeichnung: Nectin-2/PVRL2/CD112

Hintergrund:

Description: Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+?T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.

Name: CD112,Nectin-2,PVRL2,PVRL2

Gen-ID: 19294

UniProt: P32507-1