LI Cadherin Protein (His tag)

Produktnummer ABIN7533976

Dieses Recombinant LI Cadherin-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für LI Cadherin Protein (His tag) (ABIN7533976)

Target: LI Cadherin

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 90 % by SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses LI Cadherin Protein ist gelabelt mit His tag.

Verwendungszweck: Active Recombinant Human CDH17/LI-cadherin Protein

Sequenz: QEGKFSGPLK PMTFSIYEGQ EPSQIIFQFK ANPPAVTFEL TGETDNIFVI EREGLLYYNR ALDRETRSTH NLQVAALDAN GIIVEGPVPI TIKVKDINDN RPTFLQSKYE GSVRQNSRPG KPFLYVNATD LDDPATPNGQ LYYQIVIQLP MINNVMYFQI NNKTGAISLT REGSQELNPA KNPSYNLVIS VKDMGGQSEN SFSDTTSVDI IVTENIWKAP KPVEMVENST DPHPIKITQV RWNDPGAQYS LVDKEKLPRF PFSIDQEGDI YVTQPLDREE KDAYVFYAVA KDEYGKPLSY PLEIHVKVKD INDNPPTCPS PVTVFEVQEN ERLGNSIGTL TAHDRDEENT ANSFLNYRIV EQTPKLPMDG LFLIQTYAGM LQLAKQSLKK QDTPQYNLTI EVSDKDFKTL CFVQINVIDI NDQIPIFEKS DYGNLTLAED TNIGSTILTI QATDADEPFT GSSKILYHII KGDSEGRLGV DTDPHTNTGY VIIKKPLDFE TAAVSNIVFK AENPEPLVFG VKYNASSFAK FTLIVTDVNE APQFSQHVFQ AKVSEDVAIG TKVGNVTAKD PEGLDISYSL RGDTRGWLKI DHVTGEIFSV APLDREAGSP YRVQVVATEV GGSSLSSVSE FHLILMDVND NPPRLAKDYT GLFFCHPLSA PGSLIFEATD DDQHLFRGPH FTFSLGSGSL QNDWEVSKIN GTHARLSTRH TEFEEREYVV LIRINDGGRP PLEGIVSLPV TFCSCVEGSC FRPAGHQTGI PTVGM

Spezifität: Gln23-Met787

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 1μg/mL (100 μL/well) can bind anti Human CDH17 antibody with a linear range of 0.01-20ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: LI Cadherin

Andere Bezeichnung: CDH17/LI-cadherin

Hintergrund:

Description: This protein is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Name: CDH16, HPT-1, HPT1,CDH17,HPT-1,HPT1

Gen-ID: 1015

UniProt: Q12864