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IgG2a Protein

Recombinant IgG2a-Protein exprimiert in HEK-293 Cells.
Produktnummer ABIN7536588

Kurzübersicht für IgG2a Protein (ABIN7536588)

Target

IgG2a

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

Human

Quelle

HEK-293 Cells

Reinheit

> 97 % by SDS-PAGE.
  • Verwendungszweck

    Active Recombinant Human IgG2A Protein

    Sequenz

    ERKCCVECPP CPAPPVAGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVQFNWYV DGVEVHNAKT KPREEQFNST FRVVSVLTVV HQDWLNGKEY KCKVSNKGLP APIEKTISKT KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDISV EWESNGQPEN NYKTTPPMLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK

    Spezifität

    Glu99-Lys326

    Sterilität

    0.22 μm filtered

    Endotoxin-Niveau

    <0.1EU/μg

    Biological Activity Comment

    Measured by its binding ability in a functional ELISA.Immobilized Human CD32a at 2 μg/mL (100 μL/well) can bind Human IgG2 with a linear range of 1.2-338 ng/mL.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target

    IgG2a

    Substanzklasse

    Antibody

    Hintergrund

    Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens

    Name: IGHG2,Immunoglobulin heavy constant gamma 2,IgG2

    Gen-ID

    3501

    UniProt

    P01859
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