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CCL13 Protein

CCL13 Spezies: Human Wirt: Yeast (Pichia pastoris) Recombinant > 95 % by SDS-PAGE.
Produktnummer ABIN7536003
  • Target Alle CCL13 Proteine anzeigen
    CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 2
    • 2
    Human
    Quelle
    • 11
    • 1
    • 1
    • 1
    • 1
    Yeast (Pichia pastoris)
    Verwendungszweck
    Recombinant Human CCL13/MCP-4 Protein
    Sequenz
    QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
    Spezifität
    Gln24-Thr98
    Reinheit
    > 95 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    <0.1EU/μg
    Top Product
    Discover our top product CCL13 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
    Andere Bezeichnung
    CCL13/MCP-4 (CCL13 Produkte)
    Synonyme
    CKb10 Protein, MCP-4 Protein, NCC-1 Protein, NCC1 Protein, SCYA13 Protein, SCYL1 Protein, C-C motif chemokine ligand 13 Protein, chemokine (C-C motif) ligand 13 Protein, CCL13 Protein
    Hintergrund

    Description: Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chemokines, CCL13 binds to several chemokine receptors (CCR1, CCR2 and CCR3), allowing it to elicit different effects on its target cells. A number of studies have shown that CCL13 is involved in many chronic inflammatory diseases, in which it functions as a pivotal molecule involved in the selective recruitment of cell lineages to the inflamed tissues and their subsequent activation. MCP-4/CCL13 is secreted from chondrocytes and activates the proliferation of rheumatoid synovial cells, thereby leading to joint destruction in RA.

    Name: CCL13,CKb10,MCP-4,NCC-1,NCC1,SCYA13,SCYL1

    Gen-ID
    6357
    UniProt
    Q99616
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Phosphorylierungen bei SARS-CoV-2 Infektion
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