DKK3 Protein (AA 1-349) (His tag)

Produktnummer ABIN7505749

Dieses Recombinant DKK3-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für DKK3 Protein (AA 1-349) (His tag) (ABIN7505749)

Target: DKK3

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-349

Aufreinigungstag / Konjugat: Dieses DKK3 Protein ist gelabelt mit His tag.

Sequenz: Met1-Ile349

Produktmerkmale: A DNA sequence encoding the Mouse DKK3 protein (Q9QUN9) (Met1-Ile349) was expressed with a C-His.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: DKK3

Hintergrund:

Abbreviation: DKK3

Target Synonym: AW061014,C87148

Background: DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

Molekulargewicht:

Calculated MW: 38.28 kDa

Observed MW: 60 kDa

UniProt: Q9QUN9